Patient connects the headset to their mobile or tablet and stimulates using the Flow app.
Clinician remotely monitors progress and adjusts treatment plan based on weekly results.
Can be used in combination with antidepressants or talking therapy.
Clinical trial data shows tDCS is more effective when combined with SSRIs2.
57% in remission at 10 weeks in clinical trial.
Twice as effective as the 21 best selling antidepressants, measured using an odds ratio1.
Depression lowers the activity in the pre-frontal cortex of the brain.
Flow works by using tDCS (transcranial Direct Current Stimulation) to stimulate the brain and help restore activity to relieve depressive symptoms, improving motivation, mood, sleep and concentration.
Patients can use their headset at-home through a controlled app on their mobile or tablet. Clinicians have full remote access and oversight of patient adherence and progress.
Remission rates in our clinical trial show 57% are depression-free at 10 weeks1.
Efficacy is superior to antidepressants; using an odds ratio to measure the difference in effect between treatment and placebo, Flow has an odds ratio of 3.45 Vs Antidepressants at 1.681.
Within a few weeks, the Flow treatment is associated with supporting improvements in mood, concentration, optimism and initiative, while reducing anxiety3.
Flow’s exciting and encouraging data raise the prospect of a real advance in the treatment of depression…a helpful intervention for many people suffering from major depression.
Allan Young
Chair of Mood Disorders, King’s College London
Flow’s results show a clear separation of active and sham treatment in a large, multisite randomised controlled trial… a very promising development in mental health treatment.
Corey Keller
Assistant Professor of Psychiatry and Behavioural Sciences, Stanford University
Flow has gained popularity among our patients [in NHS pilots]. This positive reception speaks volumes about the effectiveness and patient satisfaction associated with Flow.
Dr Azhar Zafar
GPA Director of Research, NHS GP
If the patient has a poor response to antidepressants, I add Flow to the treatment plan. The modalities empower each other. We have grown our business with Flow.
Katrin Orav
Psychiatrist, Sensus
Home-based treatment that is safe and evidence-based. A major step forward for patients with depression.
Sophia Frangou, MD PhD
Professor of Psychiatry, Mount Sinai & Editor-in-Chief of European Psychiatry
With Flow’s brain stimulation headset our highly respected experts now have a new tool to treat depression.
Elena Touroni, PhD
Clinical Director, Chelsea Psychology Clinic
Flow has provided an additional means of treatment for our clinics and has increased our client base for both stand alone Flow users and as an add on to our TMS service.
BrainState TMS Clinic
We work with clinics to provide them Flow headsets, at commercial rates.
Oversee treatment plans with weekly monitoring sessions, by accessing patient data in your Clinic Portal.
Purchase your own headsets, and invite patients into clinic to stimulate.
There have been 0 serious side effects reported in our real world base of 12,000 users, or our clinical trial.
2% of users get minor effects - the most common are skin irritation and headaches.
Yes. Flow is often used alongside antidepressants, talking therapy, TMS and other therapies. Many patients use Flow to taper off their medication under medical supervision.
Many of our clinics have had success using Flow to treat patients with treatment resistant depression. Some are also experimenting with Flow in cases of PTSD, Bi-Polar, anxiety and addiction.
We are in the process of publishing our clinical trial data. It will be publicly available in Autumn 2023.
1 Double-blinded, placebo-controlled clinical trial (n=173) to measure the effectiveness and safety of Flow’s at-home tDCS depression treatment (2023).
2 2013 – Brunoni et al., The sertraline vs. electrical current therapy for treating depression clinical study: results from a factorial, randomized, controlled trial. JAMA Psychiatry. Apr;70(4):383-91
3 Data on file